Prevalence and patterns of chromosomal abnormalities among Egyptian patients with infertility: a single institution’s 5-year experience
نویسندگان
چکیده
Abstract Background Chromosomal abnormalities represent an important cause of human infertility. Little is known about the prevalence chromosomal among Egyptian couples with We estimated cytogenetic profiles and semen analysis patterns infertile couples. analyzed data from medical archives 2150 patients infertility in Mansoura University Children’s Hospital, Egypt 2015 to 2019. The included karyotypes reports. Results were reported 13.5% (290/2150); 150 out 1290 (11.62%) males 140 860 (16.28%) females. Within males, numerical detected 134/1290 (10.38%) structural found 16/1290 (1.24%) males. females, sex chromosome 75/860 (8.72%) 31/860 (3.6%) mosaicism was 22/860 (2.56%) male pseudohermaphrodites 12/860 (1.39%) Conclusions Numerical aberrations are most frequent Attention should be paid traditional as diagnostic step work-up.
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ژورنال
عنوان ژورنال: Middle East Fertility Society Journal
سال: 2022
ISSN: ['1110-5690', '2090-3251']
DOI: https://doi.org/10.1186/s43043-022-00101-x